Quantifying the Relationships among Drug Classes
نویسندگان
چکیده
منابع مشابه
Quantifying the Relationships among Drug Classes
The similarity of drug targets is typically measured using sequence or structural information. Here, we consider chemo-centric approaches that measure target similarity on the basis of their ligands, asking how chemoinformatics similarities differ from those derived bioinformatically, how stable the ligand networks are to changes in chemoinformatics metrics, and which network is the most reliab...
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ژورنال
عنوان ژورنال: Journal of Chemical Information and Modeling
سال: 2008
ISSN: 1549-9596,1549-960X
DOI: 10.1021/ci8000259